CompagOs
Platform

Bon3OID blends bioprinting, mechanics, and imaging

The Bon3OID™ platform is a robust, reproducible framework that captures key aspects of human bone biomechanics and remodeling while enabling scalable preclinical and translational workflows with defined functional endpoints.

Bon3OID modelBon3OID microscopy animation
Bioprinted bone organoids
Human cell-based, mineralized bone constructs derived from healthy or disease-relevant sources.
Mechanical loading
Controlled cyclic loading to support bone formation, remodeling, and functional maturation.
Functional readouts
Micro-CT, histology, and molecular analyses to generate quantitative structural, cellular, and molecular endpoints.
Impact

Value across the research pipeline

Bon3OID generates functional, human-relevant bone biology endpoints that support confident decisions across preclinical and translational research.

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Researchers

Generate early, human-relevant efficacy and mechanism data that supports clear go/no-go decisions in bone-focused drug development.

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Translational teams

Align preclinical findings with translational hypotheses by linking functional bone biology to disease-relevant and patient-derived models.

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Clinical outlook

Test translational hypotheses by revealing longitudinal functional bone signals early.

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Payers

Support downstream value discussions by enabling earlier insight into treatment response in bone-related diseases.

Resources

Latest resources

Recent publications and posters supporting Bon3OID.

All resources
Creating Mechanically Loaded Human-derived Osteosarcoma Organoids for Disease Modeling and Drug Testing
Poster

Creating Mechanically Loaded Human-derived Osteosarcoma Organoids for Disease Modeling and Drug Testing

Human Bone Organoids with Osteoclastic Activity: Emulating Fracture Phenotypes in an in vitro Model of Bone Remodeling
Poster

Human Bone Organoids with Osteoclastic Activity: Emulating Fracture Phenotypes in an in vitro Model of Bone Remodeling